An incredible discovery shocked science and if it were to serve people it would mark an important step for humanity. Even the desire for eternal youth would not only be an illusion, but a reality.
Is about a scientific breakthrough that was developed in the laboratory of molecular biologist David Sinclair at Harvard Medical School, where experts managed to make old mice young again.
According to the media ‘CNN’, this effect was achieved “using proteins that can convert an adult cell into a stem cell”, so “Sinclair and his team have restored aged cells in mice to earlier versions of themselves”.
and although the group of scientists had published their first advance in 2020, it was not until this year that their experiments began to bear fruit.
It’s a permanent reset, as far as we know, and we think it may be a universal process that could be applied throughout the body to reset our age
David Sinclair, who has been working for the last 20 years to obtain the coveted ‘eternal youth’ formula, speaking to an audience at Life Itself, a health and wellness event presented in association with ‘CNN’ said: “It is a permanent reset, as far as we know, and we think it may be a universal process that could be applied throughout the body to reset our age.”
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In addition, he added: “If we reverse aging, some diseases should not occur. Today we have the technology to be able to reach 100 years and beyond without worrying about having cancer at 70, heart disease at 80 and Alzheimer’s at 90.”
“This is the world that is coming. It is literally a question of when and for most of us it will happen in our lives,” he said.
This was joined by Whitney Casey, an investor who teamed up with the expert Sinclair so that the next step is to create a home test.
“His research shows that you can change aging so that life is younger for longer. Now he wants to change the world and turn aging into a disease,” Casey said.
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The memory returns; no more dementia. I believe that in the future, delaying and reversing aging will be the best way to treat diseases
The purpose of the research is to attack aging as the disease that causes the deterioration of the entire body.
“We know that when we reverse the age of an organ like the brain of a mouse, the diseases of aging disappear. The memory returns; there is no more dementia. I think that in the future, delaying and reversing aging will be the best way to treat the diseases that afflict most of us,” said David Sinclair.
How did they achieve this effect in mice?
It is no secret to anyone that millions of investigations that have tried to understand aging and how to reverse it.
However, so far, they have not been successful. In some studies, even animals that were exposed to genetic alterations developed cancerous tumors.
So, to avoid these side effects, Sinclair’s lab geneticist Yuancheng Lu used a discovery by Japanese biophysicist Dr. Shinya Yamanaka, who won a Nobel Prize with it in 2007.
As reported by ‘CNN’, “this scientist managed to reprogram adult human skin cells to behave like embryonic or pluripotent stem cells.” This finding became known as “Yamanaka factors”.
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So Yuancheng Lu decided to use three of these four factors and, in addition, he gave the mice a harmless virus, which was going to be in charge of “administering Yamanaka’s rejuvenating factors”.
After a while, the geneticist gave the mouse an antibiotic to activate the embryonic stem cells. Surprisingly, the animal began to have improvements in its body and some parts of it were rejuvenated.
“The antibiotic is just a tool. It could be any chemical really, just a way to make sure all three genes are turned on,” Sinclair said.
“Normally they are only turned on in very young developing embryos and then turn off as we get older,” he explained.
And now we can harness a reset switch that restores the cell’s ability to read the genome correctly again, as if it were young.
Furthermore, he added: “Somehow, the cells know that the body can reboot itself and still know which genes should be active when they were young.”
“I call it the information theory of aging. (…) It is a loss of information, which leads aging cells to forget how they work, to forget what type of cell they are. And now we can harness a reset switch that restores the cell’s ability to read the genome correctly again, as if it were young.”
This advance confirms how close science is to finding a way to understand aging, stop it and, in the best of cases, reverse it.
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Scientists manage to reverse aging in mice